L. Bruneau, J. Derezinski Pauli-Fierz Hamiltonians defined as quadratic forms (revised version) (337K, Postscript) ABSTRACT. We study Pauli-Fierz Hamiltonians---self-adjoint operators describing a small quantum system interacting with a bosonic field. Using quadratic form techniques, we extend the results of Derezinski-Gerard and Gerard about the self-adjointness, the location of the essential spectrum and the existence of a ground state to a large class of Pauli-Fierz Hamiltonians.